Hepatitis

Hepatitis A virus hepatitis A belongs to the family of Picornaviridae, and gender Hepatovirus. Has not capped icosahedral form of approximately 28 nm in diameter and a single linear RNA genome of positive guidance. The genome has a total length of 7.5 kb which is translated into a polyprotein alone, but alone can cause an infection. The polyprotein is cut in several locations producing capsular proteins VP1, VP2, VP3 and VP4, and nonstructural proteins. In its 5 'end is covalently linked protein, VPg, which serves as the cap 5' protecting eukaryotic genomes genome by the end. Its 3 'by contrast has an area polyadenylated (poly (A)) which also makes security duties in addition to allowing its translation by the machinery of the host cell. This is a virus that is rarely found in countries with high standards of hygiene.The virus is very resistant to high temperatures, acids and alkalis (eg, soaps and other cleaning products).